| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6983650 | Colloids and Surfaces B: Biointerfaces | 2013 | 7 Pages |
Abstract
- Raloxifene HCl (RH) was loaded into solid lipid nanoparticles using double emulsion method.
- A mixture of aqueous and organic solvents was employed as W1 phase of double emulsion system.
- Nanoparticles were formed with mean particle size of 180Â nm and loading efficiency of 4.5%.
- Release studies were performed by measuring the remained entrapped drug instead of dissolved drug amount.
- Antiproliferative studies revealed that SLNs could provide more cytotoxic effects in comparison with free drug.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Mohsen Nabi-Meibodi, Alireza Vatanara, Abdolhossein Rouholamini Najafabadi, Mohammad Reza Rouini, Vahid Ramezani, Kambiz Gilani, Seyed Mohammad Hossein Etemadzadeh, Kayhan Azadmanesh,