| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6983660 | Colloids and Surfaces B: Biointerfaces | 2013 | 38 Pages |
Abstract
- A novel hydrophobic, biodegradable and biocompatible poly(ortho ester) copolymer was synthesized to prepare celecoxib-loaded nanoparticles for intraocular therapy.
- Celecoxib-loaded poly(ortho ester) nanoparticles were prepared using a double emulsion solvent diffusion method.
- Stable and transparent emulsions were achieved with efficient encapsulation efficiencies.
- Poly(ortho ester) nanoparticles can efficiently deliver therapeutics for prolonged periods of time, with desirable properties such as smaller size, high encapsulation efficiency, zero-order release profiles and cytocompatibility.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Mallika Palamoor, Monica M. Jablonski,