Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6983676 | Colloids and Surfaces B: Biointerfaces | 2013 | 5 Pages |
Abstract
- Nanoparticles can cross blood-brain-barrier and target amyloidogenic structures.
- AuNPs affect the protein structure and dynamics of insulin fibril for aggregation.
- AuNPs delayed amyloid-like fibrils formation by about 1 week.
- AuNPs disrupt fibrillogenesis resulting in fibrils are shorter and more compact.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Shuchen Hsieh, Chiung-wen Chang, Hsuan-hung Chou,