Fabrication and reduction-sensitive behavior of polyion complex nano-micelles based on PEG-conjugated polymer containing disulfide bonds as a potential carrier of anti-tumor paclitaxel

- A reduction-sensitive drug carrier has been fabricated for the delivery of anti-cancer paclitaxel.
- The polyion complexation of hydrophilic chains contributed to higher stability of assemblies in aqueous media.
- The assembled micelle showed the advantages of potential passive targeting to tumor, reduction-sensitive controlled release, and so on.