Article ID Journal Published Year Pages File Type
6984076 Colloids and Surfaces B: Biointerfaces 2012 11 Pages PDF
Abstract
► Non-solvent crystallisation is potential to prepare lactose particles with favourable properties. ► The poorer the flowability of lactose powders the lower drug emission from inhaler device. ► Reduction in drug-carrier adhesion properties was obtained with engineered lactose particles. ► Lactose powders with higher bulk density showed higher amounts of drug deposited in the lung. ► Drug content uniformity for DPI formulation is depended on carrier flowability and particle size.
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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