Article ID Journal Published Year Pages File Type
6984161 Colloids and Surfaces B: Biointerfaces 2012 9 Pages PDF
Abstract
► Low-fouling carboxymethyl dextran surfaces bearing RGD and RGE were fabricated. ► PANC-1 cells clustered to form islet-like aggregates for each surface. ► Islet-like aggregates expressed insulin and glucagon after 14 days. ► Islet-like aggregates exposed to RGD surfaces were the smallest. ► Islet-like aggregates exposed to RGD surfaces had the highest insulin secretion.
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Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
Preview
In vitro morphogenesis of PANC-1 cells into islet-like aggregates using RGD-covered dextran derivative surfaces
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