Cross-linking with acid chlorides improves thermal and mechanical properties of collagen based biopolymer material

► Interacting terephthaloyl chloride with Type I collagen increases the thermal stability of the collagen based biopolymer material. ► Interacting terephthaloyl chloride with Type I collagen increases the mechanical strength of the collagen based biopolymer material. ► Cross-linking chemistry between -COCl- groups of terephthaloyl chloride with -NH2 group of collagen via nucleophilic addition elimination reaction.