Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7080434 | Bioresource Technology | 2013 | 8 Pages |
Abstract
In this study, efficient polymer-grade l-lactic acid production was achieved with the strain Bacillus sp. P38 by using cellulosic hydrolysate as the sole carbon source. In fed-batch fermentation, 180 g Lâ1l-lactic acid was obtained with a volumetric productivity of 2.4 g Lâ1 hâ1 and a yield of 0.96 g gâ1 total reducing sugars. No d-isomer of lactic acid was detected in the broth. Strain P38 tolerated up to 10 g Lâ1 2-furfural, and lactate production was sharply inhibited only when the 2-furfural concentration was higher than 6 g Lâ1. Moreover, strain P38 also tolerated high concentrations (>6 g Lâ1) of other fermentation inhibitors in cellulosic hydrolysate, such as vanillin and acetic acid, although it was slightly sensitive to formic acid. The efficient l-lactic acid production, combined with high inhibitor tolerance and efficient pentose utilization, indicate that Bacillus sp. P38 is a promising producer of polymer-grade l-lactic acid from cellulosic biomass.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Process Chemistry and Technology
Authors
Lili Peng, Limin Wang, Chengchuan Che, Ge Yang, Bo Yu, Yanhe Ma,