Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7082423 | Bioresource Technology | 2013 | 27 Pages |
Abstract
Volumetric mass transfer coefficient (kLa) is a key fermentation parameter for the production of docosahexaenoic acid (DHA) from glycerol by Schizochytrium sp. S31. In order to elucidate the effects of kLa on the fermentations, both baffled and unbaffled flask cultures and fed-batch cultures were developed in present work. The results showed that high kLa could effectively increase the DHA concentration, DHA productivity and conversion yield (Yx/s, g/g). When kLa was set at 1802 ± 105 hâ1 in the fed-batch culture, DHA concentration was achieved at 28.93 g/L, DHA productivity at 301 mg/L/h and Yx/s at 0.44 ± 0.02 g/g, all of which were significantly higher than those in the previous similar studies.
Related Topics
Physical Sciences and Engineering
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Authors
Guifang Chang, Nisi Gao, Guiwei Tian, Qinghang Wu, Ming Chang, Xingguo Wang,