Article ID Journal Published Year Pages File Type
7084876 Bioresource Technology 2013 5 Pages PDF
Abstract
► Two artificial operons carrying PmHAS and precursors genes consist expression system. ► A novel two-stage induction strategy was established according to constructed system. ► Hyaluronic acid accumulated 6.8 g/L in shake flask by expressing GlcUA independently. ► Sizes of hyaluronic acid can be controlled by time of induction of precursors and HAS. ► Uniform hyaluronic acid of varying sizes gained here all reached considerable yields.
Related Topics
Physical Sciences and Engineering Chemical Engineering Process Chemistry and Technology
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