| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7085599 | Bioresource Technology | 2012 | 9 Pages |
Abstract
⺠Two continuous culture strategies, CCCM and CCCD, were developed in the Pichia pastoris. ⺠Cell concentration is a key parameter for PGL over-production in the P. pastoris. ⺠Kinetic parameters for controlling cell density by CCCM and CCCD culture were solved. ⺠The CCCM culture exhibited higher PGL productivity and cell viability. ⺠Using the continuous mode, protease accumulation was decreased.
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Authors
Huilin Wang, Jianghua Li, Long Liu, Xiaoman Li, Dongxu Jia, Guocheng Du, Jian Chen, Jiangning Song,