Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7087840 | Bioresource Technology | 2012 | 4 Pages |
Abstract
⺠Schizophyllum commune could be used for biotransformation of flavone in Fructus sophorae. ⺠Sophoricoside was firstly metabolized to compound (2), and then to compound (3) and (4). ⺠The content of compound (2) was increased by more than 30-fold by biotransformation. ⺠New compound (3) had cytotoxic activity with an IC50 of 12.1 nmol/ml against MCF-7 cells.
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Authors
Jianguo Wu, Xialu Yang, Juan Ge, Yiping Zhang, Lin Wu, Jianmiao Liu, Xiaoyu Zhang,