Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
710706 | IFAC Proceedings Volumes | 2009 | 6 Pages |
Abstract
AbstractThe study of protein folding and its ramifications in biological contexts is at the heart of computational biology. In this paper, we discuss a number of tools in systems engineering that would provide an analysis framework to help explain the observed dynamic behavior of the protein, ultimately making the connection between protein structure and functionality. A case study of villin headpiece folding using principal components analysis as well as clustering demonstrates the potential of these tools in responding to this challenge.
Related Topics
Physical Sciences and Engineering
Engineering
Computational Mechanics
Authors
Ahmet Palazoglu, Yaman Arkun, Burak Erman, Attila Gursoy,