Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7120902 | Measurement | 2018 | 14 Pages |
Abstract
A portable high-resolution microscope based on combination of fiber-optic array (FOA) and pre-amplification lens, which can overcome the magnification limit of FOA, was developed. By employing the amplification lens at the small-end of the FOA, the resolution was improved from 4.4â¯Î¼m to 1.0â¯Î¼m over a field of view (FOV) of 140â¯Î¼mâ¯Ãâ¯100â¯Î¼m without using any algorithm processing, and the distortion only slightly increases from 0.13% to 0.19%. The distortion is still lower than that of normal lens-based microscopy. Moreover, the combination methods of the amplification lens and FOA were investigated, which including only FOA, the pre-amplification lens at the small-end of the FOA (termed preAL-FOA) and the post-amplification lens at the big-end of FOA (termed postAL-FOA). The result proved the best resolution was achieved by using the preAL-FOA This microscopy is suitable for real-time monitoring of cells in microfluidic systems.
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Physical Sciences and Engineering
Engineering
Control and Systems Engineering
Authors
Weiming Wang, Yan Yu, Hui Huang,