Improvement of estimation parameter for frame-rate analysis of blood flow using laser speckle image sensing

Improved estimation parameters are proposed for frame-rate analysis of blood flow in skin tissue and a blood vessel using laser speckle image sensing. These parameters are introduced for visualizing a blood flow distribution with improving image quality and computation time or with reducing effects of a speckle contrast and random noises. Experiments were conducted for sample models using ground-glass plates and fluid flow, human finger, human wrist and an anesthetized rat to confirm the feasibility of the proposed parameters.