Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7133325 | Sensors and Actuators A: Physical | 2018 | 9 Pages |
Abstract
Adapting medical technology for use at the point of care, demands the development of portable, robust and accurate systems for the early diagnosis and monitoring of a wide range of diseases. Microscopy at the point of care, fueled by recent advances in micro-optics, micro-electronics and micro-electromechanical systems, is an emerging and promising field. However, imaging devices already developed remain rather sophisticated and bulky, mainly because of failure to address the most challenging technical limitation: to combine large field-of-view (FOV) with high resolution imaging of biological specimens. To address this need, we developed a portable, optical scanning microsystem that can image - with approximately 1â¯Î¼mâ¯resolution- large areas (6â¯mmâ¯Ãâ¯40â¯mm) from various biological samples. This is achieved through the use of a microfabricated - 2D lens array that scans a sample in 1 direction in few minutes. We demonstrated that our system can image blood smear and identify single white blood cells immobilized in a microfluidic chip.
Related Topics
Physical Sciences and Engineering
Chemistry
Electrochemistry
Authors
Georgia Korompili, Georgios Kanakaris, Christos Ampatis, Nikos Chronis,