Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7134433 | Sensors and Actuators A: Physical | 2016 | 17 Pages |
Abstract
This paper reports on the first demonstration of polymeric microfluidic cantilever sensors. Microcantilever sensors, magnetic beads, and microfluidic technology have been combined to create a polymer based biosensor. Using cheap materials like polyimide, a simple fabrication method has been developed to produce cantilevers with an embedded microfluidic channel. The advantage of this approach is that the addition of a microfluidic channel enables the analysis of smaller volumes and increases the capture efficiency in applications detecting rare analytes. As a proof of principle the system has been applied for the detection of the waterborne protozoan parasite Cryptosporidium, achieving sensitivity comparable to QCM, whereas a previous set-up without the microfluidic channel was unable to detect the parasite.
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Authors
Helen Bridle, Wenxing Wang, Despoina Gavriilidou, Farid Amalou, Duncan P. Hand, Wenmiao Shu,