Dependable Model for Enzyme Kinetics using Petri Networks

In this paper we propose a dependable model for single substrate enzyme kinetics based on the differential Petri network formalism. Metabolic signaling pathways contain biochemical reactions in which substrates are catalyzed enzymatic and turn them into active biochemical products. The enzyme reactions are described quantitatively through ordinary differential equations (ODEs) in the proposed Petri network model. The specificity of the biochemical reactions are captured in the proposed Petri network model. The simulation study shows qualitative validation of the dependability of the proposed Petri network model with experimental results for enzyme kinetics.