Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7206988 | Journal of the Mechanical Behavior of Biomedical Materials | 2018 | 8 Pages |
Abstract
In the ACLT model, weight-bearing stress was modified in the ZOI. This disruption of the stress pattern induced alterations of the tissues composing the bone-cartilage unit. In term of mechanical properties, all tissues exhibited changes. The most affected tissue was the most superficial: hyaline cartilage displayed the strongest relative decrease (42%) followed by calcified cartilage (37%) and cortical plate was slightly modified (16%). This supports the hypotheses that PTOA initiates in the hyaline cartilage.
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Physical Sciences and Engineering
Engineering
Biomedical Engineering
Authors
Sarah Pragnère, Caroline Boulocher, Ophélie Pollet, Catherine Bosser, Aurélie Levillain, Magali Cruel, Thierry Hoc,