Article ID Journal Published Year Pages File Type
7207886 Journal of the Mechanical Behavior of Biomedical Materials 2016 13 Pages PDF
Abstract

- Response to varying matrix mechanics is significant in case of aggressive breast cancer cells.
- Increased secretion of VEGF by breast cancer cells when seeded on stiffer matrices.
- Inhibition of ROCK activity reduces the secretion of VEGF by cancer cells.
Keywords
Related Topics
Physical Sciences and Engineering Engineering Biomedical Engineering
Preview
Breast cancer cells mechanosensing in engineered matrices: Correlation with aggressive phenotype
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