| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7208172 | Journal of the Mechanical Behavior of Biomedical Materials | 2016 | 13 Pages |
Abstract
- Novel type of liquid crystalline substrates (OPC) with tunable storage modulus were fabricated.
- OPC mimic in vivo extracellular matrix by exhibiting viscoelasticity and liquid crystalline state.
- NIH/3T3s were highly sensitive to the elasticity of OPC substrates.
- NIH/3T3s responded to mechanical stimuli of OPC substrates probably through paxillin-ERK pathway.
- OPC substrates with intermediate modulus facilitated cellular adhesion and proliferation.
Keywords
Related Topics
Physical Sciences and Engineering
Engineering
Biomedical Engineering
Authors
Yang Chen, Lei Wang, Hao Huang, Ruizhe Tan, Jupeng Zhao, Shenyu Yang, Rong Zeng, Hao Wu, Jiaqing Zhang, Bin Yu, Mei Tu,