Simulation of the effect of spot size on temperature field and weld forming in laser tissue welding

Laser Biological Tissue Welding is a great potential for tissue suture replacement technology. However, most of the biological tissue laser welding research focused on the chronic histology after laser irradiation, the lack of systematic analysis of laser parameters and other related factors on the impact of tissue welding anastomosis effect. In this work, in order to understand the heat transfer and heat distribution, a two-layer structure model of skin was developed and validated with the experimental results, which is based on the theory of bio-heat transfer. Under the condition of different spot sizes, the temperature response of the model, including the peak temperature, the temperature field distribution and the time behavior, were calculated according to the Gaussian distribution laser heat source. We evaluated the effect of changes in laser spot size on the thermal denaturation zone produced during laser skin welding. The calculated result basically in good agreement with the experimental result indicated that the developed model was validity and reasonable.