Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7229444 | Biosensors and Bioelectronics | 2018 | 32 Pages |
Abstract
By introduction of Mo metal species (molybdenum-based polyoxometalates) into the Cu-MOF as co-precursor, molybdenum carbide nanosphere (MoxC@C) was prepared via a simple calcining routine and a further etching the metallic Cu process. The obtained MoxC@C showed a unique structure where well-dispersed MoxC nanoparticles (NPs) were encapsulated in porous carbon matrix. As-fabricated novel 3D porous architecture MoxC@C nanosphere exhibited a potent and persistent electro-oxidation behavior followed by well-separated oxidation peaks (peak to peak voltage is about 350â¯mV) toward adenine (A) and guanine (G) by differential pulse voltammetry (DPV). This excellent electrochemical performance can be attributed to the unique structure and composition of 3D MoxC@C. Furthermore, 3D MoxC@C also revealed high selectivity and sensitivity, good reproducibility, excellent stability and anti-interference ability. The calibration curves for quantitive analysis of G and A were obtained: 0.03-122â¯ÂµM, and 0.02-122â¯ÂµM, respectively, the detection limits were 0.0085â¯ÂµM, 0.008â¯ÂµM, respectively. The proposed procedure was successfully applied to detect G and A in human urine and serum samples with satisfactory recovery, which manifests its viability application for practical analysis.
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Authors
Lei Zhang, Jing Zhang,