Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7229568 | Biosensors and Bioelectronics | 2018 | 23 Pages |
Abstract
In current work highly sensitive and stable electrochemical sensor for simultaneous non-enzymatic detection of epinephrine (EP), L-tyrosine (L-Tyr) is constructed based on Electron beam irradiated Polypyrrole (EB-Ppy) nanospheres (Zeta potential 33.69â¯mV at pH 7) embedded over bovine serum albumin (BSA) (Zeta potential ââ¯11.54â¯mV at pH 7) porous structure, fabricated by simple chemical routes. The BSA structure has the advantages of large surface area, excellent structure stability, rich pore channels and redox mediator role. The constructed sensor exhibited excellent sensor performances by the combination of protein with NH group and recorded the linear response of EP, L-Tyr individual in the concentration range of 100â¯nM-1â¯mM, 100â¯nM-800â¯Î¼M, with detection limit 7.1â¯nM, 8.8â¯nM (S/Nâ¯=â¯3Ï/b). The EB-Ppy-BSA/GCE electrochemical sensor manifests intriguing application with good sensitivity, selectivity and reproducibility towards the EP, L-Tyr detection. The practical analytical utility provides great promise by selective measurements in tea, and chicken extract which has a promising future for biological and healthcare applications.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
R. Ramya, P. Muthukumaran, J. Wilson,