| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7231540 | Biosensors and Bioelectronics | 2016 | 4 Pages |
Abstract
In this paper, gold-silver nanoparticle (AuNP-AgNP) heterodimers were assembled with highly yield as an active SERS substrate, based on antigen-antibody immunoreaction. The developed SERS sensor has successful achieved the ultrasensitive detection of folic acid (FA) with the limit of detection (LOD) as 0.86Â pg/mL. And the linear range was from 0.005Â ng/mL to 1Â ng/mL. The results also demonstrated that this developed method showed high specificity and excellent recovery for the human serum samples, indicating its promising potential in bio-diagnosis and the environmental monitoring.
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Authors
Xiaoling Wu, Xi Chen, Fengli Gao, Wei Ma, Liguang Xu, Hua Kuang, Aike Li, Chuanlai Xu,