| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7231830 | Biosensors and Bioelectronics | 2015 | 6 Pages |
Abstract
Dopamine (DA) is a neurotransmitter which plays a key role in the life science. Self-assembled Au@Ag nanorod dimers based on aptamers were developed for ultrasensitive dopamine detection. The electronic field was significantly enhanced by the addition of silver shell coating on the surface of Au NR dimer. The results displayed that Au@Ag NR dimers were ideal building blocks for constructing the SERS substrates with prominent Raman enhancement effects. It was found that with using this Surface-enhanced Raman scattering (SERS)-encoded this sensing system, a limit of detection of 0.006Â pM and a wide linear range of 0.01-10Â pM for dopamine detection were obtained. Our work open up a new avenue for the diagnosis and drug-discovery programs.
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Authors
Lijuan Tang, Si Li, Fei Han, Liqiang Liu, Liguang Xu, Wei Ma, Hua Kuang, Aike Li, Libing Wang, Chuanlai Xu,