Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7232208 | Biosensors and Bioelectronics | 2015 | 5 Pages |
Abstract
A graphene oxide-based fluorescent nanosensor AGO has been designed and synthesized by covalent grafting allylamine onto GO surface. In aqueous media, AGO displays a highly selective and sensitive discrimination of Fe3+ from Fe2+ and other metal ions through electron transfer-induced fluorescence quenching. The quenching of AGO fluorescence is linearly proportional to Fe3+ concentration in a wide range of 0-120 μM (correlation coefficient R2=0.9994). Moreover, AGO can be used to construct a combinational three-input logic gate to discriminate Fe3+ and Fe2+. The logic gate works well in intracellular fluorescence imaging, which shows a potential as a promising platform for biosensing analysis.
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Authors
Liang He, Jianna Li, John H. Xin,