| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7233369 | Biosensors and Bioelectronics | 2014 | 5 Pages |
Abstract
Acrylic acid 3-acetyl-2-oxo-2 H-chromen-7-yl ester (ACA) was rationally designed and synthesized as a simple and effective fluorescent probe for sensing cysteine with high selectivity and naked-eye detection. The probe can detect cysteine by fluorescence spectrometry with a detection limit of 0.657 μM and can be used with calf serum and in live cell imaging. The conjugate addition/cyclization sequence mechanism of the reaction between ACA and cysteine was conï¬rmed by ESI-MS and fluorescence spectra.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Xi Dai, Qing-Hua Wu, Peng-Chong Wang, Jie Tian, Yu Xu, Sheng-Qing Wang, Jun-Ying Miao, Bao-Xiang Zhao,