Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7233601 | Biosensors and Bioelectronics | 2014 | 7 Pages |
Abstract
We report the development of a new aptasensor scheme for detecting small molecules in solution. We detect binding to the target 17β-estradiol in the low nanomolar range by observing changes in the size and surface potential of nanoparticle-aptamer conjugates when the aptamers adopt a folded conformation around the target.
Related Topics
Physical Sciences and Engineering
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Analytical Chemistry
Authors
Omar A. Alsager, Shalen Kumar, Geoff R. Willmott, Kenneth P. McNatty, Justin M. Hodgkiss,