Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7233637 | Biosensors and Bioelectronics | 2014 | 5 Pages |
Abstract
A direct electrochemical detection of quercetin based on functionalized graphene oxide modified on gold-printed circuit board chip was demonstrated in this study. Functionalized graphene oxide materials are prepared by the covalent reaction of graphene oxide with silver@silica-polyethylene glycol nanoparticles (~12.35Â nm). Functionalized graphene oxide electrode shows a well-defined voltammetric response in phosphate buffered saline and catalyzes the oxidation of quercetin to quinone without the need of an enzyme. Significantly, the functionalized graphene oxide modified electrode exhibited a higher sensitivity than pristine gold-printed circuit board and graphene oxide electrodes, a wide concentration range of 7.5 to 1040Â nM and detection limit of 3.57Â nM. Developed biosensor platform is selective toward quercetin in the presence of an interferent molecule.
Related Topics
Physical Sciences and Engineering
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Analytical Chemistry
Authors
Murugan Veerapandian, Yeong-Tai Seo, Kyusik Yun, Min-Ho Lee,