Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7234131 | Biosensors and Bioelectronics | 2013 | 6 Pages |
Abstract
An octachlorostyrene (OCS) photoelectrochemical (PEC) immunosensor was developed by cross-linking anti-OCS antibody onto a CdTe/CdS-sensitized TiO2 nanotube arrays (NTAs). The anti-OCS polyclonal antibody was developed in rabbit as a result of immunization with BSA-OCS hapten conjugate. TiO2 NTAs were immobilized firstly with hydrothermally synthesized CdTe quantum dots (QDs), and then CdS which filled the spaces within the CdTe-TiO2 composite and encapsulated the CdTe QDs, forming an ideal stepwise bandedge structure, which benefited the light harvesting. The PEC immunosensor therefore shows high specificity and high sensitivity with a limit of detection of 2.58Â pM, and a linear range from 5Â pM to 50Â nM. The testing time is 4Â min. The analysis of river water reveals that the proposed sensor can be applied in the analysis of OCS in real water samples without complicated pre-treatments.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jin Cai, Pengtao Sheng, Liping Zhou, Lei Shi, Niya Wang, Qingyun Cai,