Article ID Journal Published Year Pages File Type
7234557 Biosensors and Bioelectronics 2013 6 Pages PDF
Abstract
► We report a label-free biosensor for the detection of target DNA. ► A DNAzyme-linked hairpin structure was designed as signal probe. ► The DNAzyme activity depends on the hairpin opening due to the three-way (target-hairpin-assistant) junction. ► This strategy exhibits high discrimination ability even against single-base mismatch.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
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