Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7234557 | Biosensors and Bioelectronics | 2013 | 6 Pages |
Abstract
⺠We report a label-free biosensor for the detection of target DNA. ⺠A DNAzyme-linked hairpin structure was designed as signal probe. ⺠The DNAzyme activity depends on the hairpin opening due to the three-way (target-hairpin-assistant) junction. ⺠This strategy exhibits high discrimination ability even against single-base mismatch.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Shurong Tang, Ping Tong, Heng Li, Fang Gu, Lan Zhang,