| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7238798 | Nanomedicine: Nanotechnology, Biology and Medicine | 2018 | 27 Pages |
Abstract
Nanoparticle-based system for cell type-specific delivery of selective kinase inhibitor was developed. The system enabled specific inhibition of epidermal growth factor signaling in hepatic myofibroblasts, the major driver of liver cancer development, and elicited cancer chemoprevention effect with reduced drug dose and toxicities.163
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Authors
Manjeet PhD, Shigeki MD, PhD, Takaaki MD, PhD, Adam PhD, Anu BS, Marina PhD, Anna P BA, Nicolas MD, MSc, Hadassa BA, C Billie BA, Naoto MD, PhD, Atsushi MD, PhD, Hiroki Hoshida, Mohamed El-Abtah, Noor B Ahmad, Amaia PhD, Roberto PhD, Bryan C PhD,