Article ID Journal Published Year Pages File Type
724083 IFAC Proceedings Volumes 2007 6 Pages PDF
Abstract

Metabolic Flux Analysis was performed to identify the significant metabolic reactions for hybridoma cells during batch and fed-batch culture. Correlation analysis yielded the factors that influence biomass growth and productivity and elucidated the nature of the relationship between them. Consequently, an integrated dynamic model expressing the rate of consumption and production of nutrients/metabolites and the biomass growth and decline was developed.

Related Topics
Physical Sciences and Engineering Engineering Computational Mechanics
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