Article ID Journal Published Year Pages File Type
7278554 Biological Psychology 2015 37 Pages PDF
Abstract
Our results suggest that two different sub-regions of the amygdala and their respective neural networks are affected in OCD: the superficial amygdala and networks related to evaluation of reinforcers and risk anticipation and the basolateral amygdala which is implicated in fear processing. The diminished CBT response in patients showing a lower degree centrality of the basolateral amygdala reflects a deficient fear circuit in these patients which may impact fear extinction as a core mechanism of exposure-based CBT.
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Life Sciences Neuroscience Behavioral Neuroscience
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