| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7279368 | Brain, Behavior, and Immunity | 2018 | 17 Pages |
Abstract
Fish oil feeding decreases neuroinflammatory gene expression in response to amyloid-β. Neither amyloid-β infusion or increasing brain DHA affects the brain concentrations of specialized pro-resolving mediators in this model, or the concentrations of most other eicosanoids and docosanoids.
Keywords
HDHAICVintracerebroventricularcPLA2TLRTSPOEicosanoidPD1EPAiPLA2LC/MS/MSArachidonic acidEicosapentaenoic aciddocosahexaenoic acidhydroxyeicosatetraenoic acidPolyunsaturated fatty acidsPUFANeuroinflammationinflammationOmega-3 polyunsaturated fatty acidsinterleukinAlzheimer’s diseaseToll-like receptorcluster of differentiationARADHAFish oilcytosolic phospholipase A2TREMlipoxygenasemajor histocompatibility complexMHCHETELipid mediatortranslocator proteinprostaglandinliquid chromatography tandem mass spectrometry
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Authors
Kathryn E. Hopperton, Marc-Olivier Trépanier, Nicholas C.E. James, Raphaël Chouinard-Watkins, Richard P. Bazinet,