| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7279421 | Brain, Behavior, and Immunity | 2018 | 12 Pages |
Abstract
These data suggest 11β-HSD1 deficiency attenuates the hippocampal pro-inflammatory response to LPS, associated with increased capacity for aerobic glycolysis and mitochondrial ATP generation. This may provide better metabolic support and be neuroprotective during systemic inflammation or aging.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Manu Verma, Tiina M.J. Kipari, Zhenguang Zhang, Tak Yung Man, Thorsten Forster, Natalie Z.M. Homer, Jonathan R. Seckl, Megan C. Holmes, Karen E. Chapman,