Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7280895 | Brain, Behavior, and Immunity | 2015 | 5 Pages |
Abstract
Our findings show that ECT influences the TRP-KYN pathway, with a shift in TRP-KYN metabolites balance towards molecules with neuroprotective properties correlating with antidepressant effects of ECT; thereby providing a first line of evidence that the mechanism of action of ECT is (co)mediated by the TRP-KYN pathway.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Sinan Guloksuz, Baer Arts, Sharon Walter, Marjan Drukker, Laura Rodriguez, Aye-Mu Myint, Markus J. Schwarz, Rudolf Ponds, Jim van Os, Gunter Kenis, Bart P.F. Rutten,