Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling

Article ID	Journal	Published Year	Pages	File Type
7281490	Brain, Behavior, and Immunity	2014	17 Pages	PDF

Abstract

Our data show that neuropathic pain induces a cluster of depressive-like symptoms and profound hippocampal plasticity that are dependent on TNF signaling through TNFR1.

Keywords

TNFR1 TNF Depression Neuropathic pain Cytokines Myelin Neurogenesis Plasticity

Related Topics

Life Sciences Immunology and Microbiology Immunology

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Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling

Authors

Anna Dellarole, Paul Morton, Roberta Brambilla, Winston Walters, Spencer Summers, Danielle Bernardes, Mariagrazia Grilli, John R. Bethea,