Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7283618 | Brain and Language | 2018 | 6 Pages |
Abstract
Picture naming is a language task that involves multiple neural networks and is used to probe aphasia-induced language deficits. The pattern of neural activation seen in healthy individuals during picture naming is disrupted in individuals with aphasia, but the time-course of the disruption remains unclear. Specifically, it remains unclear which anatomical and temporal aspects of neural processing are necessary for correct naming. Here, we tested two individuals with stroke induced aphasia, and compared the differences in the event-related potentials (ERPs) and current sources when they made correct vs. erroneous responses during picture naming. The pre-articulatory ERP activity was significantly different between the two responses. Current source analysis revealed that the ability to recruit left temporal and frontal areas within a 300-550â¯ms time window after stimulus onset contributed to correct responses. These results suggest that targeted neuromodulation in these areas could lead to better treatment outcomes in patients with aphasia.
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Authors
Tarkeshwar Singh, Lorelei Phillip, Roozbeh Behroozmand, Ezequiel Gleichgerrcht, Vitória Piai, Julius Fridriksson, Leonardo Bonilha,