Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7299153 | Neurobiology of Learning and Memory | 2016 | 10 Pages |
Abstract
Ibotenate lesioning of ventral subiculum produced significant impairment of performance in the Morris water maze and reduced the hippocampal neurogenesis in rats. Post lesion exposure to C.T. restored the hippocampal neurogenesis and improved the spatial memory functions in VSL rats. Our study supports the hypothesis that the combination paradigm is critical towards the development of an enhanced behavioral and cognitive experience especially in conditions of CNS insults and the associated cognitive dysfunctions.
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Authors
Vijayakumar Kapgal, Neethi Prem, Preethi Hegde, T.R. Laxmi, Bindu M. Kutty,