| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7300928 | Neurobiology of Learning and Memory | 2012 | 12 Pages |
Abstract
⺠Pctk1, Ccnd1 or Tcf12 overexpression all had an effect on learning and memory. ⺠Pctk1, Tcf12, and Ccnd1 in hippocampus produced spatial working memory deficits. ⺠Expression of Ccnd1 and Tcf12 produced spatial reference memory deficits. ⺠LTD induced by low frequency stimulation was absent in Pctk1 treated animals. ⺠Tcf12 also produced neurodegeneration and tumors in CA1 and dentate gyrus.
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Authors
Ke Wu, Shoudong Li, Karthik Bodhinathan, Craig Meyers, Weijun Chen, Martha Campbell-Thompson, Lauren McIntyre, Thomas C. Foster, Nicholas Muzyczka, Ashok Kumar,