Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7301158 | Neurobiology of Learning and Memory | 2011 | 8 Pages |
Abstract
⺠We compared extinction of appetitive operant lever pressing across 14 mouse strains. ⺠Strength of extinction is not correlated with the acquisition of operant performance. ⺠Extinction has a heritable component, expressed by high inter-strain variability. ⺠C3H and BxD-27 can serve as models for cognitive flexibility. ⺠Perseverative lines NOD, BxD-16 and -42 may be used to model compulsive food-seeking.
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Authors
Hemi A.I. Malkki, Laura A.B. Donga, Sabine E. de Groot, NeuroBSIK Mouse Phenomics Consortium NeuroBSIK Mouse Phenomics Consortium, Francesco P. Battaglia, Cyriel M.A. Pennartz,