Article ID Journal Published Year Pages File Type
7303341 Neuroscience & Biobehavioral Reviews 2015 14 Pages PDF
Abstract
A neurobiological model that incorporates these propositions is presented, with a focus on the potential for N-methyl-d-aspartate receptor antagonism and glutathione augmentation as potential adjunctive pharmacotherapies to treat the comorbidity. While this review highlights the importance of alcohol monitoring and reduction strategies in the treatment of bipolar disorder, the clinical impact of the proposed model remains limited by the lack of controlled trials of novel pharmacological interventions.
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