Article ID Journal Published Year Pages File Type
7303640 Neuroscience & Biobehavioral Reviews 2015 9 Pages PDF
Abstract

- Developmental delays are common to many monogenic intellectual disability and autistic disorders.
- Animal models reveal delayed and transient impairments at the level of the synapse.
- Many impairments occur within known critical periods for normal brain development.
- Temporal expression patterns of affected genes may underlie developmental phenotypes directly or indirectly.
- Dysregulated critical periods could unify other key hypotheses underlying these disorders.
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
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