Article ID Journal Published Year Pages File Type
7319020 Neuropsychologia 2016 7 Pages PDF
Abstract
In Parkinson's disease patients and healthy controls, anticipation of the imminent movement of a target object significantly decreased reaction time, movement duration, and increased maximum movement velocity. The increase of maximum movement velocity in the escape-condition was significantly more pronounced for Parkinson's disease patients as compared to healthy controls. We provide evidence that internal cues such as temporal constraints are sufficient to diminish the cardinal clinical symptom of bradykinesia in Parkinson's disease. Our results suggest that expectations rather than sensory cues are critical for the emergence of paradoxical kinesia and we discuss the implications of our findings for an account of paradoxical kinesia.
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