Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7320403 | Neuropsychologia | 2015 | 10 Pages |
Abstract
Abnormalities in the neural networks underlying social cognition and emotional processing can be detected prior to clinical diagnosis in Huntington's disease. Connectivity between the amygdala and other brain regions is impacted by the disease process in pre-manifest HD and may therefore be a useful way of identifying participants who are approaching a clinical diagnosis. Furthermore, the “Reading the Mind in the Eyes Test” is a surrogate measure of amygdala function that is clinically useful across the entire cross-section of disease stages in HD.
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Authors
Sarah L. Mason, Jiaxiang Zhang, Faye Begeti, Natalie Valle Guzman, Alpar S. Lazar, James B. Rowe, Roger A. Barker, Adam Hampshire,