The basic principles of topology-dynamics relations in networks: An empirical approach

Here we report a simulation approach to this problem based on the analysis of the relationship between dissipation kinetics across the network of a perturbative stimulus applied on a single node and its topological properties. The empirical character of the study prompted us to rely on real biological networks instead of 'ideal architectures' and to adopt a statistical attitude with a relatively low number of affected nodes for each network that is much more realistic in real-world biological applications. The analysis allowed us to recognize some general topology-dynamics correlation rules variously modulated by global wiring architecture.