| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7502861 | Drug and Alcohol Dependence | 2018 | 8 Pages |
Abstract
Low-frequency and rare exonic variants with large effects do not play a major role in alcohol and tobacco use, nor does the aggregate effect of ExomeChip variants. However, our results confirmed the role of the CHRNA5-CHRNA3-CHRNB4 cluster of nicotinic acetylcholine receptor subunit genes in tobacco use.
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Authors
Andries T. Marees, Anke R. Hammerschlag, Lisa Bastarache, Hilde de Kluiver, Florence Vorspan, Wim van den Brink, Dirk J. Smit, Damiaan Denys, Eric R. Gamazon, Ruifang Li-Gao, Elemi J. Breetvelt, Mark C.H. de Groot, Tessel E. Galesloot, Sita H. Vermeulen,