Chronic restraint stress during withdrawal increases vulnerability to drug priming-induced cocaine seeking via a dopamine D1-like receptor-mediated mechanism

Article ID	Journal	Published Year	Pages	File Type
7503070	Drug and Alcohol Dependence	2018	8 Pages	PDF

Abstract

Exposure to chronic stress during early withdrawal may confer lasting vulnerability to some types of relapse, and dopamine D1-like receptors appear to mediate both chronic stress effects on cocaine seeking and extinction of cocaine seeking.

Keywords

MPFC infralimbic D1R MDMA D1-like receptor 3,4-methylenedioxymethamphetamine Stress Abstinence Reinstatement Dopamine relapse medial prefrontal cortex conditioned stimuli fixed ratio Cocaine

Related Topics

Life Sciences Neuroscience Behavioral Neuroscience

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Chronic restraint stress during withdrawal increases vulnerability to drug priming-induced cocaine seeking via a dopamine D1-like receptor-mediated mechanism

Authors

Kevin T. Ball, Eric Stone, Olivia Best, Tyler Collins, Hunter Edson, Erin Hagan, Salvatore Nardini, Phelan Neuciler, Michael Smolinsky, Lindsay Tosh, Kristin Woodlen,